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1-Piperidine Propionic Acid as an Allosteric Inhibitor of Protease Activated Receptor-2

In the last decades, studies on the inflammatory signaling pathways in multiple pathological contexts have revealed new targets for novel therapies. Among the family of G-protein-coupled Proteases Activated Receptors, PAR2 was identified as a driver of the inflammatory cascade in many pathologies, r...

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Detalles Bibliográficos
Autores principales: Chinellato, Monica, Gasparotto, Matteo, Quarta, Santina, Ruvoletto, Mariagrazia, Biasiolo, Alessandra, Filippini, Francesco, Spiezia, Luca, Cendron, Laura, Pontisso, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610151/
https://www.ncbi.nlm.nih.gov/pubmed/37895957
http://dx.doi.org/10.3390/ph16101486