Toll-like Receptor Ligands Enhance Vaccine Efficacy against a Virulent Newcastle Disease Virus Challenge in Chickens

To enhance the efficacy of the current Newcastle disease vaccine, we have selected potential adjuvants that target well-characterized pattern recognition receptors: the toll-like receptors (TLRs). Imiquimod is a small-molecule activator of TLR7, which is a sensor of dsDNA. ODN-1826 is a mimetic of C...

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Detalles Bibliográficos
Autores principales: Lee, Chang-Won, Bakre, Abhijeet, Olivier, Timothy L., Alvarez-Narvaez, Sonsiray, Harrell, Telvin L., Conrad, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610171/
https://www.ncbi.nlm.nih.gov/pubmed/37887747
http://dx.doi.org/10.3390/pathogens12101230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610171/
https://www.ncbi.nlm.nih.gov/pubmed/37887747
http://dx.doi.org/10.3390/pathogens12101230

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