Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease

Based on the multi-target-directed ligands (MTDLs) approach, two series of tryptanthrin derivatives with benzenesulfonamide substituents were evaluated as multifunctional agents for the treatment of Alzheimer’s disease (AD). In vitro biological assays indicated most of the derivatives had good choli...

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Detalles Bibliográficos
Autores principales: Wang, Guoxing, Du, Jiyu, Ma, Jie, Liu, Peipei, Xing, Siqi, Xia, Jucheng, Dong, Shuanghong, Li, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610214/
https://www.ncbi.nlm.nih.gov/pubmed/37895939
http://dx.doi.org/10.3390/ph16101468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610214/
https://www.ncbi.nlm.nih.gov/pubmed/37895939
http://dx.doi.org/10.3390/ph16101468

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