Tributyrin Mitigates Ethanol-Induced Lysine Acetylation of Histone-H3 and p65-NFκB Downregulating CCL2 Expression and Consequent Liver Inflammation and Injury

Purpose: Chemokine-driven leukocyte infiltration and sustained inflammation contribute to alcohol-associated liver disease (ALD). Elevated hepatic CCL2 expression, seen in ALD, is associated with disease severity. However, mechanisms of CCL2 regulation are not completely elucidated. Post-translation...

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Detalles Bibliográficos
Autores principales: Ghare, Smita S., Charpentier, Benjamin T., Ghooray, Dushan T., Zhang, Jingwen, Vadhanam, Manicka V., Reddy, Sreelatha, Joshi-Barve, Swati, McClain, Craig J., Barve, Shirish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610222/
https://www.ncbi.nlm.nih.gov/pubmed/37892472
http://dx.doi.org/10.3390/nu15204397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610222/
https://www.ncbi.nlm.nih.gov/pubmed/37892472
http://dx.doi.org/10.3390/nu15204397

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