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Combination of Phenethyl Isothiocyanate and Dasatinib Inhibits Hepatocellular Carcinoma Metastatic Potential through FAK/STAT3/Cadherin Signalling and Reduction of VEGF Secretion

Cancerous cells are characterised by their ability to invade, metastasise, and induce angiogenesis. Tumour cells use various molecules that can be targeted to reverse these processes. Dasatinib, a potent Src inhibitor, has shown promising results in treating hepatocellular carcinoma (HCC) in vitro a...

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Detalles Bibliográficos
Autores principales: Strusi, Gabriele, Suelzu, Caterina M., Weldon, Shannon, Giffin, Jennifer, Münsterberg, Andrea E., Bao, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610226/
https://www.ncbi.nlm.nih.gov/pubmed/37896150
http://dx.doi.org/10.3390/pharmaceutics15102390