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Combination of Phenethyl Isothiocyanate and Dasatinib Inhibits Hepatocellular Carcinoma Metastatic Potential through FAK/STAT3/Cadherin Signalling and Reduction of VEGF Secretion
Cancerous cells are characterised by their ability to invade, metastasise, and induce angiogenesis. Tumour cells use various molecules that can be targeted to reverse these processes. Dasatinib, a potent Src inhibitor, has shown promising results in treating hepatocellular carcinoma (HCC) in vitro a...
Autores principales: | Strusi, Gabriele, Suelzu, Caterina M., Weldon, Shannon, Giffin, Jennifer, Münsterberg, Andrea E., Bao, Yongping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610226/ https://www.ncbi.nlm.nih.gov/pubmed/37896150 http://dx.doi.org/10.3390/pharmaceutics15102390 |
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