Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic variability. Our earlier work focused on the discover...

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Detalles Bibliográficos
Autores principales: Tyagi, Puneet, Patel, Chandresh, Gibson, Kimberly, MacDougall, Fiona, Pechenov, Sergei Y., Will, Sarah, Revell, Jefferson, Huang, Yue, Rosenbaum, Anton I., Balic, Kemal, Maharoof, Umar, Grimsby, Joseph, Subramony, J. Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610252/
https://www.ncbi.nlm.nih.gov/pubmed/37896196
http://dx.doi.org/10.3390/pharmaceutics15102436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610252/
https://www.ncbi.nlm.nih.gov/pubmed/37896196
http://dx.doi.org/10.3390/pharmaceutics15102436

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