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Design, Synthesis, and Biological Evaluation of a Novel [(18)F]-Labeled Arginine Derivative for Tumor Imaging

To better diagnose and treat tumors related to arginine metabolism, (2S,4S)-2-amino-4-(4-(2-(fluoro-(18)F)ethoxy)benzyl)-5-guanidinopentanoic acid ([(18)F]7) was designed and prepared by introducing [(18)F]fluoroethoxy benzyl on carbon-4 of arginine. [(18)F]7 and 7 were successfully prepared using s...

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Detalles Bibliográficos
Autores principales: Huang, Yong, Li, Chengze, Li, Zhongjing, Xie, Yi, Chen, Hualong, Li, Shengli, Liang, Ying, Wu, Zehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610273/
https://www.ncbi.nlm.nih.gov/pubmed/37895948
http://dx.doi.org/10.3390/ph16101477