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Clinical Pharmacology of Vinpocetine: Properties Revisited and Introduction of a Population Pharmacokinetic Model for Its Metabolite, Apovincaminic Acid (AVA)

This paper examines the use of vinpocetine in the context of clinical pharmacology. The main and active metabolite of vinpocetine is apovincaminic acid (AVA). Due to the scarce information in the literature on AVA pharmacokinetics, we propose a population pharmacokinetic (PopPK) model for AVA based...

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Detalles Bibliográficos
Autores principales: Petric, Zvonimir, Paixão, Paulo, Filipe, Augusto, Guimarães Morais, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610279/
https://www.ncbi.nlm.nih.gov/pubmed/37896263
http://dx.doi.org/10.3390/pharmaceutics15102502