Osteolytic Bone Loss and Skeletal Deformities in a Mouse Model for Early-Onset Paget’s Disease of Bone with PFN1 Mutation Are Treatable by Alendronate

A novel osteolytic disorder due to PFN1 mutation was discovered recently as early-onset Paget’s disease of bone (PDB). Bone loss and pain in adult PDB patients have been treated using bisphosphonates. However, therapeutic strategies for this specific disorder have not been established. Here, we eval...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Zhu, Aini, Hailati, Kajikawa, Shuhei, Shirakawa, Jumpei, Tsuji, Kunikazu, Asou, Yoshinori, Koga, Hideyuki, Sekiya, Ichiro, Nifuji, Akira, Noda, Masaki, Ezura, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610320/
https://www.ncbi.nlm.nih.gov/pubmed/37895866
http://dx.doi.org/10.3390/ph16101395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610320/
https://www.ncbi.nlm.nih.gov/pubmed/37895866
http://dx.doi.org/10.3390/ph16101395

Ejemplares similares