Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan

Chronic, low-grade inflammation has been implicated in aging and age-dependent conditions, including Alzheimer’s disease, cardiomyopathy, and cancer. One of the age-associated processes underlying chronic inflammation is protein aggregation, which is implicated in neuroinflammation and a broad spect...

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Detalles Bibliográficos
Autores principales: Kakraba, Samuel, Ayyadevara, Srinivas, Mainali, Nirjal, Balasubramaniam, Meenakshisundaram, Bowroju, Suresh, Penthala, Narsimha Reddy, Atluri, Ramani, Barger, Steven W., Griffin, Sue T., Crooks, Peter A., Shmookler Reis, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610358/
https://www.ncbi.nlm.nih.gov/pubmed/37895969
http://dx.doi.org/10.3390/ph16101498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610358/
https://www.ncbi.nlm.nih.gov/pubmed/37895969
http://dx.doi.org/10.3390/ph16101498

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