The Amorphous Solid Dispersion of Chrysin in Plasdone(®) S630 Demonstrates Improved Oral Bioavailability and Antihyperlipidemic Performance in Rats

Chrysin is a flavonoid with various biological activities. However, its low water solubility and strong metabolism render its oral bioavailability rather poor. This study aimed to develop a stable solid dispersion formulation of chrysin to improve the dissolution of chrysin, so as to increase its or...

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Detalles Bibliográficos
Autores principales: Wang, Chenhui, Liu, Xiaowei, Zhao, Ruihan, Yang, Meiqing, Liu, Wenqian, Dai, Qiuyang, Bao, Xiaofeng, Chen, Yong, Ma, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610386/
https://www.ncbi.nlm.nih.gov/pubmed/37896138
http://dx.doi.org/10.3390/pharmaceutics15102378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610386/
https://www.ncbi.nlm.nih.gov/pubmed/37896138
http://dx.doi.org/10.3390/pharmaceutics15102378

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