Cargando…
Predicting Maternal and Infant Tetrahydrocannabinol Exposure in Lactating Cannabis Users: A Physiologically Based Pharmacokinetic Modeling Approach
A knowledge gap exists in infant tetrahydrocannabinol (THC) data to guide breastfeeding recommendations for mothers who use cannabis. In the present study, a paired lactation and infant physiologically based pharmacokinetic (PBPK) model was developed and verified. The verified model was used to simu...
Autores principales: | Shenkoya, Babajide, Yellepeddi, Venkata, Mark, Katrina, Gopalakrishnan, Mathangi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610403/ https://www.ncbi.nlm.nih.gov/pubmed/37896227 http://dx.doi.org/10.3390/pharmaceutics15102467 |
Ejemplares similares
-
Mechanistic Modeling of Maternal Lymphoid and Fetal Plasma Antiretroviral Exposure During the Third Trimester
por: Shenkoya, Babajide, et al.
Publicado: (2021) -
Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain
por: Gazarov, Emely A., et al.
Publicado: (2023) -
Predicting Resolvin D1 Pharmacokinetics in Humans with Physiologically‐Based Pharmacokinetic Modeling
por: Yellepeddi, Venkata K., et al.
Publicado: (2020) -
Les effets épigénétiques du cannabis/tétrahydrocannabinol()
por: Costentin, J.
Publicado: (2020) -
Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures
por: Gilder, Mary Ellen, et al.
Publicado: (2018)