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RNAi-Mediated Knockdown of Cottontail Rabbit Papillomavirus Oncogenes Using Low-Toxicity Lipopolyplexes as a Paradigm to Treat Papillomavirus-Associated Cancers

The cottontail rabbit papillomavirus (CRPV)-associated VX2 carcinoma of the New Zealand White rabbit serves as a model system for human papillomavirus (HPV)-associated head and neck squamous cell carcinomas (HNSCCs). The aim of this study was to evaluate the tumor-inhibiting effect of RNAi-mediated...

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Detalles Bibliográficos
Autores principales: Ali, Uzma, Bette, Michael, Ambreen, Ghazala, Pinnapireddy, Shashank R., Tariq, Imran, Marquardt, André, Stuck, Boris A., Bakowsky, Udo, Mandic, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610439/
https://www.ncbi.nlm.nih.gov/pubmed/37896139
http://dx.doi.org/10.3390/pharmaceutics15102379