Identification of Andrographolide as an Agonist of Bile Acid TGR5 Receptor in a Cell Line to Demonstrate the Reduction in Hyperglycemia in Type-1 Diabetic Rats

Andrographolide (ADG) is contained in bitter plants, and its effects are widely thought to be associated with taste receptors. The current study used animal studies and cell lines to investigate the role of ADG in diabetic models. The Takeda G-protein-coupled receptor (TGR5) was directly influenced...

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Detalles Bibliográficos
Autores principales: Li, Yingxiao, Cheng, Kai-Chun, Liu, I-Min, Cheng, Juei-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610544/
https://www.ncbi.nlm.nih.gov/pubmed/37895888
http://dx.doi.org/10.3390/ph16101417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610544/
https://www.ncbi.nlm.nih.gov/pubmed/37895888
http://dx.doi.org/10.3390/ph16101417

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