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The Expression Kinetics and Immunogenicity of Lipid Nanoparticles Delivering Plasmid DNA and mRNA in Mice

In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and transporting the mRNA payload into host cells. Despite their prominence in mRNA vaccines, there remains a notable gap in...

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Detalles Bibliográficos
Autores principales: Zhang, Wanyue, Pfeifle, Annabelle, Lansdell, Casey, Frahm, Grant, Cecillon, Jonathon, Tamming, Levi, Gravel, Caroline, Gao, Jun, Thulasi Raman, Sathya N., Wang, Lisheng, Sauve, Simon, Rosu-Myles, Michael, Li, Xuguang, Johnston, Michael J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610642/
https://www.ncbi.nlm.nih.gov/pubmed/37896985
http://dx.doi.org/10.3390/vaccines11101580