A human mucosal melanoma organoid platform for modeling tumor heterogeneity and exploring immunotherapy combination options

Mucosal melanoma (MM), an aggressive rare subtype of melanoma, is distinct from cutaneous melanoma and has poor prognoses. We addressed the lack of cell models for MM by establishing 30 organoids of human oral MM (OMM), which retained major histopathological and functional features of parental tumor...

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Detalles Bibliográficos
Autores principales: Sun, Lulu, Kang, Xindan, Ju, Houyu, Wang, Chong, Yang, Guizhu, Wang, Rui, Sun, Shuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610903/
https://www.ncbi.nlm.nih.gov/pubmed/37889972
http://dx.doi.org/10.1126/sciadv.adg6686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610903/
https://www.ncbi.nlm.nih.gov/pubmed/37889972
http://dx.doi.org/10.1126/sciadv.adg6686

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