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High-throughput synthesis provides data for predicting molecular properties and reaction success

The generation of attractive scaffolds for drug discovery efforts requires the expeditious synthesis of diverse analogues from readily available building blocks. This endeavor necessitates a trade-off between diversity and ease of access and is further complicated by uncertainty about the synthesiza...

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Detalles Bibliográficos
Autores principales: Götz, Julian, Jackl, Moritz K., Jindakun, Chalupat, Marziale, Alexander N., André, Jérôme, Gosling, Daniel J., Springer, Clayton, Palmieri, Marco, Reck, Marcel, Luneau, Alexandre, Brocklehurst, Cara E., Bode, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610918/
https://www.ncbi.nlm.nih.gov/pubmed/37889964
http://dx.doi.org/10.1126/sciadv.adj2314