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IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance

Hematopoietic stem cells (HSCs) are tightly controlled to maintain a balance between blood cell production and self-renewal. While inflammation-related signaling is a critical regulator of HSC activity, the underlying mechanisms and the precise functions of specific factors under steady-state and st...

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Detalles Bibliográficos
Autores principales: Rundberg Nilsson, Alexandra J. S., Xian, Hongxu, Shalapour, Shabnam, Cammenga, Jörg, Karin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610924/
https://www.ncbi.nlm.nih.gov/pubmed/37889967
http://dx.doi.org/10.1126/sciadv.adg5391