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IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance
Hematopoietic stem cells (HSCs) are tightly controlled to maintain a balance between blood cell production and self-renewal. While inflammation-related signaling is a critical regulator of HSC activity, the underlying mechanisms and the precise functions of specific factors under steady-state and st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610924/ https://www.ncbi.nlm.nih.gov/pubmed/37889967 http://dx.doi.org/10.1126/sciadv.adg5391 |