Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow

New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))–response modeling to transcriptomic changes in the liver of mice and in fathead minnow larvae after short-term exposures (7 days and 1 day, respectively) to several dose...

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Detalles Bibliográficos
Autores principales: Martin, Rubia, Hazemi, Monique, Flynn, Kevin, Villeneuve, Daniel, Wehmas, Leah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611195/
https://www.ncbi.nlm.nih.gov/pubmed/37888672
http://dx.doi.org/10.3390/toxics11100820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611195/
https://www.ncbi.nlm.nih.gov/pubmed/37888672
http://dx.doi.org/10.3390/toxics11100820

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