IV BCG Vaccination and Aerosol BCG Revaccination Induce Mycobacteria-Responsive γδ T Cells Associated with Protective Efficacy against M. tb Challenge

Intravenously (IV) delivered BCG provides superior tuberculosis (TB) protection compared with the intradermal (ID) route in non-human primates (NHPs). We examined how γδ T cell responses changed in vivo after IV BCG vaccination of NHPs, and whether these correlated with protection against aerosol M....

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Detalles Bibliográficos
Autores principales: Morrison, Alexandra L., Sarfas, Charlotte, Sibley, Laura, Williams, Jessica, Mabbutt, Adam, Dennis, Mike J., Lawrence, Steve, White, Andrew D., Bodman-Smith, Mark, Sharpe, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611416/
https://www.ncbi.nlm.nih.gov/pubmed/37897006
http://dx.doi.org/10.3390/vaccines11101604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611416/
https://www.ncbi.nlm.nih.gov/pubmed/37897006
http://dx.doi.org/10.3390/vaccines11101604

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