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Single-cell mass cytometric analysis of peripheral immunity and multiplex plasma marker profiling of non-small cell lung cancer patients receiving PD-1 targeting immune checkpoint inhibitors in comparison with platinum-based chemotherapy

INTRODUCTION: The effect of platinum-based chemotherapy (Chem.) and second- or multiple- line immune checkpoint PD-1 blocking therapy by Nivolumab or Pembrolizumab (ICI) was assayed in the peripheral blood of non-small cell lung cancer (NSCLC) patients. METHODS: Flow cytometry was used to detect NSC...

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Detalles Bibliográficos
Autores principales: Neuperger, Patrícia, Szalontai, Klára, Gémes, Nikolett, Balog, József Á., Tiszlavicz, László, Furák, József, Lázár, György, Puskás, László G., Szebeni, Gábor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611454/
https://www.ncbi.nlm.nih.gov/pubmed/37901220
http://dx.doi.org/10.3389/fimmu.2023.1243233