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Impact of patient characteristics on innate immune responses and inflammasome activation in ex vivo human lung tissues infected with influenza A virus

BACKGROUND: Influenza A virus (IAV) infection poses a persistent global health challenge, necessitating a nuanced grasp of host immune responses for optimal interventions. While the interplay between aging, immunosenescence, and IAV is recognized as key in severe lower respiratory tract infections,...

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Detalles Bibliográficos
Autores principales: Huang, Chung-Guei, Wu, Yi-Cheng, Hsieh, Ming-Ju, Lin, Ya-Jhu, Hsieh, Tzu-Hsuan, Huang, Po-Wei, Yang, Shu-Li, Tsao, Kuo-Chien, Shih, Shin-Ru, Lee, Li-Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611511/
https://www.ncbi.nlm.nih.gov/pubmed/37900310
http://dx.doi.org/10.3389/fcimb.2023.1269329