Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75(NTR) signaling in the p75(exonIII)-KO mice

Degeneration of basal forebrain cholinergic neurons (BFCNs) is a hallmark of Alzheimer’s disease (AD). However, few mouse models of AD recapitulate the neurodegeneration of the cholinergic system. The p75 neurotrophin receptor, p75(NTR), has been associated with the degeneration of BFCNs in AD. The...

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Detalles Bibliográficos
Autores principales: Comaposada-Baró, Raquel, Benito-Martínez, Andrea, Escribano-Saiz, Juan Julian, Franco, María Luisa, Ceccarelli, Lorenzo, Calatayud-Baselga, Isabel, Mira, Helena, Vilar, Marçal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611523/
https://www.ncbi.nlm.nih.gov/pubmed/37900943
http://dx.doi.org/10.3389/fnmol.2023.1237458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611523/
https://www.ncbi.nlm.nih.gov/pubmed/37900943
http://dx.doi.org/10.3389/fnmol.2023.1237458

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