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Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer

In patients with locally advanced cancer without distant metastases, the neoadjuvant setting presents a platform to evaluate new drugs. For mismatch repair proficient/microsatellite stable (pMMR/MSS) colon and rectal cancer, immunotherapy has shown limited efficacy. Herein, we report exceptional res...

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Detalles Bibliográficos
Autores principales: Kasi, Pashtoon Murtaza, Hidalgo, Manuel, Jafari, Mehraneh D., Yeo, Heather, Lowenfeld, Lea, Khan, Uqba, Nguyen, Alana T. H., Siolas, Despina, Swed, Brandon, Hyun, Jini, Khan, Sahrish, Wood, Madeleine, Samstein, Benjamin, Rocca, Juan P., Ocean, Allyson J., Popa, Elizabeta C., Hunt, Daniel H., Uppal, Nikhil P., Garrett, Kelly A., Pigazzi, Alessio, Zhou, Xi Kathy, Shah, Manish A., Hissong, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611560/
https://www.ncbi.nlm.nih.gov/pubmed/37731056
http://dx.doi.org/10.1038/s41388-023-02835-y