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Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors

The comorbidity of autism spectrum disorder and anxiety is common, but the underlying circuitry is poorly understood. Here, Tmem74(-/-) mice showed autism- and anxiety-like behaviors along with increased excitability of pyramidal neurons (PNs) in the prelimbic cortex (PL), which were reversed by Tme...

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Detalles Bibliográficos
Autores principales: Luo, Yi-Fan, Lu, Lu, Song, Heng-Yi, Xu, Han, Zheng, Zhi-Wei, Wu, Zhou-Yue, Jiang, Chen-Chen, Tong, Chu, Yuan, Hao-Yang, Liu, Xiu-Xiu, Chen, Xiang, Sun, Mei-ling, Tang, Ya-Min, Fan, Heng-Yu, Han, Feng, Lu, Ying-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611563/
https://www.ncbi.nlm.nih.gov/pubmed/36690791
http://dx.doi.org/10.1038/s41380-023-01954-y