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Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors
The comorbidity of autism spectrum disorder and anxiety is common, but the underlying circuitry is poorly understood. Here, Tmem74(-/-) mice showed autism- and anxiety-like behaviors along with increased excitability of pyramidal neurons (PNs) in the prelimbic cortex (PL), which were reversed by Tme...
Autores principales: | Luo, Yi-Fan, Lu, Lu, Song, Heng-Yi, Xu, Han, Zheng, Zhi-Wei, Wu, Zhou-Yue, Jiang, Chen-Chen, Tong, Chu, Yuan, Hao-Yang, Liu, Xiu-Xiu, Chen, Xiang, Sun, Mei-ling, Tang, Ya-Min, Fan, Heng-Yu, Han, Feng, Lu, Ying-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611563/ https://www.ncbi.nlm.nih.gov/pubmed/36690791 http://dx.doi.org/10.1038/s41380-023-01954-y |
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