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Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes

Type 2 diabetes is a challenge in modern healthcare, and animal models are necessary to identify underlying mechanisms. The Nile rat (Arvicanthis niloticus) develops diet-induced diabetes rapidly on a conventional rodent chow diet without genetic or chemical manipulation. Unlike common laboratory mo...

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Detalles Bibliográficos
Autores principales: Anderson, Benton J., Curtis, Anne M., Jen, Annie, Thomson, James A., Clegg, Dennis O., Jiang, Peng, Coon, Joshua J., Overmyer, Katherine A., Toh, Huishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611569/
https://www.ncbi.nlm.nih.gov/pubmed/37857753
http://dx.doi.org/10.1038/s41684-023-01268-0