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Diosgenin restores memory function via SPARC-driven axonal growth from the hippocampus to the PFC in Alzheimer’s disease model mice

Central nervous system axons have minimal capacity to regenerate in adult brains, hindering memory recovery in Alzheimer’s disease (AD). Although recent studies have shown that damaged axons sprouted in adult and AD mouse brains, long-distance axonal re-innervation to their targets has not been achi...

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Detalles Bibliográficos
Autores principales: Yang, Ximeng, Tohda, Chihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611574/
https://www.ncbi.nlm.nih.gov/pubmed/37085711
http://dx.doi.org/10.1038/s41380-023-02052-9