Elevated ROS levels during the early development of Angelman syndrome alter the apoptotic capacity of the developing neural precursor cells

Angelman syndrome (AS) is a rare genetic neurodevelopmental disorder caused by the maternally inherited loss of function of the UBE3A gene. AS is characterized by a developmental delay, lack of speech, motor dysfunction, epilepsy, autistic features, happy demeanor, and intellectual disability. While...

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Detalles Bibliográficos
Autores principales: Simchi, Lilach, Gupta, Pooja Kri, Feuermann, Yonatan, Kaphzan, Hanoch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611580/
https://www.ncbi.nlm.nih.gov/pubmed/36991133
http://dx.doi.org/10.1038/s41380-023-02038-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611580/
https://www.ncbi.nlm.nih.gov/pubmed/36991133
http://dx.doi.org/10.1038/s41380-023-02038-7

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