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Elevated ROS levels during the early development of Angelman syndrome alter the apoptotic capacity of the developing neural precursor cells
Angelman syndrome (AS) is a rare genetic neurodevelopmental disorder caused by the maternally inherited loss of function of the UBE3A gene. AS is characterized by a developmental delay, lack of speech, motor dysfunction, epilepsy, autistic features, happy demeanor, and intellectual disability. While...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611580/ https://www.ncbi.nlm.nih.gov/pubmed/36991133 http://dx.doi.org/10.1038/s41380-023-02038-7 |