Does modulation of tau hyperphosphorylation represent a reasonable therapeutic strategy for Alzheimer’s disease? From preclinical studies to the clinical trials

Protein kinases (PKs) have emerged as one of the most intensively investigated drug targets in current pharmacological research, with indications ranging from oncology to neurodegeneration. Tau protein hyperphosphorylation was the first pathological post-translational modification of tau protein des...

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Detalles Bibliográficos
Autores principales: Basheer, Neha, Smolek, Tomáš, Hassan, Imtaiyaz, Liu, Fei, Iqbal, Khalid, Zilka, Norbert, Novak, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611587/
https://www.ncbi.nlm.nih.gov/pubmed/37264120
http://dx.doi.org/10.1038/s41380-023-02113-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611587/
https://www.ncbi.nlm.nih.gov/pubmed/37264120
http://dx.doi.org/10.1038/s41380-023-02113-z

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