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SIRT3 Regulates the ROS-FPR1/HIF-1α Axis under Hypoxic Conditions to Influence Lung Cancer Progression

Hypoxia-inducible factor (HIF-1α) is a therapeutic target in lung cancer, and the deacetylase sirtuin 3 (SIRT3) is closely associated with tumorigenesis. Formyl peptide receptor 1 (FPR1) is involved in a wide range of physiopathological processes in various tumor cells. We explored whether SIRT3 aff...

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Detalles Bibliográficos
Autores principales: Huang, Bo, Ding, Jie, Guo, HongRong, Wang, HongJuan, Xu, JianQun, Zheng, Quan, Zhou, LiJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611604/
https://www.ncbi.nlm.nih.gov/pubmed/37747648
http://dx.doi.org/10.1007/s12013-023-01180-x