Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs

OBJECTIVE: To test whether recombinant human diamine oxidase (rhDAO) with a mutated heparin-binding motif (mHBM), which shows an increased alpha-distribution half-life, prevents histamine-induced hemodynamic effects. MATERIAL: Thirty-eight female guinea pigs were either pretreated with rhDOA_mHBM or...

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Detalles Bibliográficos
Autores principales: Weiss-Tessbach, Matthias, Reiter, Birgit, Gludovacz, Elisabeth, Boehm, Thomas, Jilma, Bernd, Rager-Resch, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611646/
https://www.ncbi.nlm.nih.gov/pubmed/37812220
http://dx.doi.org/10.1007/s00011-023-01783-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611646/
https://www.ncbi.nlm.nih.gov/pubmed/37812220
http://dx.doi.org/10.1007/s00011-023-01783-3

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