FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination

The formation of RAD51/DMC1 filaments on single-stranded (ss)DNAs essential for homology search and strand exchange in DNA double-strand break (DSB) repair is tightly regulated. FIGNL1 AAA+++ ATPase controls RAD51-mediated recombination in human cells. However, its role in gametogenesis remains unso...

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Detalles Bibliográficos
Autores principales: Ito, Masaru, Furukohri, Asako, Matsuzaki, Kenichiro, Fujita, Yurika, Toyoda, Atsushi, Shinohara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611733/
https://www.ncbi.nlm.nih.gov/pubmed/37891173
http://dx.doi.org/10.1038/s41467-023-42576-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611733/
https://www.ncbi.nlm.nih.gov/pubmed/37891173
http://dx.doi.org/10.1038/s41467-023-42576-w

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