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Targeting the SOX2/CDP protein complex with a peptide suppresses the malignant progression of esophageal squamous cell carcinoma

Emerging evidence indicates that SOX2 is an oncogene for esophageal squamous cell carcinoma (ESCC). However, direct targeting of SOX2 is not feasible given that this transcription factor plays important roles in the maintenance of tissues such as the brain. Here, we identified CDP (Homeobox protein...

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Detalles Bibliográficos
Autores principales: Chen, Yunyun, Zhang, Kun, Zhang, Rui, Wang, Zhuo, Yang, Liang, Zhao, Tingting, Zhang, Shihui, Lin, Yong, Zhao, Hongzhou, Liu, Yongpan, Wei, Yuxuan, Zhou, Yijian, Zhang, Jiaying, Ye, Xianzong, Zhao, Jing, Li, Xinxin, Que, Jianwen, Shi, Songlin, Liu, Kuancan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611744/
https://www.ncbi.nlm.nih.gov/pubmed/37891174
http://dx.doi.org/10.1038/s41420-023-01693-7