Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density

Alzheimer’s disease begins with mild memory loss and slowly destroys memory and thinking. Cognitive impairment in Alzheimer’s disease has been associated with the localization of the microtubule-associated protein Tau at the postsynapse. However, the correlation between Tau at the postsynapse and sy...

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Detalles Bibliográficos
Autores principales: Shen, Zheng, Sun, Daxiao, Savastano, Adriana, Varga, Sára Joana, Cima-Omori, Maria-Sol, Becker, Stefan, Honigmann, Alf, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611757/
https://www.ncbi.nlm.nih.gov/pubmed/37891164
http://dx.doi.org/10.1038/s41467-023-42295-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611757/
https://www.ncbi.nlm.nih.gov/pubmed/37891164
http://dx.doi.org/10.1038/s41467-023-42295-2

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