Chronic administration of XBD173 ameliorates cognitive deficits and neuropathology via 18 kDa translocator protein (TSPO) in a mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ). It affects cognition and leads to memory impairment. The mitochondrial translocator protein (TSPO) plays an essential role in maintaining mitochondrial homeostasis and has been implicated in several neuronal dis...

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Detalles Bibliográficos
Autores principales: Pradhan, Arpit Kumar, Neumüller, Tatjana, Klug, Claudia, Fuchs, Severin, Schlegel, Martin, Ballmann, Markus, Tartler, Katharina Johanna, Pianos, Antoine, Garcia, Maria Sanchez, Liere, Philippe, Schumacher, Michael, Kreuzer, Matthias, Rupprecht, Rainer, Rammes, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611770/
https://www.ncbi.nlm.nih.gov/pubmed/37891168
http://dx.doi.org/10.1038/s41398-023-02630-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611770/
https://www.ncbi.nlm.nih.gov/pubmed/37891168
http://dx.doi.org/10.1038/s41398-023-02630-z

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