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Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry

Histone H3 lysine 9 methylation (H3K9me), which is written by the Euchromatic Histone Lysine Methyltransferases EHMT1 and EHMT2 and read by the heterochromatin protein 1 (HP1) chromobox (CBX) protein family, is dysregulated in many types of cancers. Approaches to inhibit regulators of this pathway a...

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Detalles Bibliográficos
Autores principales: Pollin, Gareth, De Assuncao, Thiago M., Doria Jorge, Salomao, Chi, Young-In, Charlesworth, M. Cristine, Madden, Benjamin, Iovanna, Juan, Zimmermann, Michael T., Urrutia, Raul, Lomberk, Gwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611923/
https://www.ncbi.nlm.nih.gov/pubmed/37782747
http://dx.doi.org/10.1042/BSR20231093