Genotyping MUltiplexed-Sequencing of CRISPR-Localized Editing (GMUSCLE): An Experimental and Computational Approach for Analyzing CRISPR-Edited Cells

Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) creates double-stranded breaks, the repair of which generates indels around the target sites. These repairs can be mono-/multi-allelic, and the editing is often random and sometimes prolonged, resul...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Abel, Laurent, Casanova, Jean-Laurent, Yang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611965/
https://www.ncbi.nlm.nih.gov/pubmed/37824834
http://dx.doi.org/10.1089/crispr.2023.0021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611965/
https://www.ncbi.nlm.nih.gov/pubmed/37824834
http://dx.doi.org/10.1089/crispr.2023.0021

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