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APOBEC Reporter Systems for Evaluating diNucleotide Editing Levels

Precision genome editing has become a reality with the discovery of base editors. Cytosine base editor (CBE) technologies are improving rapidly but are mostly optimized for TC dinucleotide targets. Here, we report the development and implementation of APOBEC Reporter Systems for Evaluating diNucleot...

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Detalles Bibliográficos
Autores principales: Rieffer, Amanda E., Chen, Yanjun, Salamango, Daniel J., Moraes, Sofia N., Harris, Reuben S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611974/
https://www.ncbi.nlm.nih.gov/pubmed/37672599
http://dx.doi.org/10.1089/crispr.2023.0027