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Exploring the Comprehensive Kozak Sequence Landscape for AAV Production in Sf9 System

The widespread successful use of recombinant Adeno-associated virus (rAAV) in gene therapy has driven the demand for scale-up manufacturing methods of vectors with optimized yield and transduction efficiency. The Baculovirus/Sf9 system is a promising platform for high yield production; however, a ma...

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Detalles Bibliográficos
Autores principales: Kondratov, Oleksandr, Zolotukhin, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612025/
https://www.ncbi.nlm.nih.gov/pubmed/37896760
http://dx.doi.org/10.3390/v15101983