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Diversity and Complexity of Internally Deleted Viral Genomes in Influenza A Virus Subpopulations with Enhanced Interferon-Inducing Phenotypes

Influenza A virus (IAV) populations harbor large subpopulations of defective-interfering particles characterized by internally deleted viral genomes. These internally deleted genomes have demonstrated the ability to suppress infectivity and boost innate immunity, rendering them promising for therape...

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Detalles Bibliográficos
Autores principales: Ghorbani, Amir, Ngunjiri, John M., Rendon, Gloria, Brooke, Christopher B., Kenney, Scott P., Lee, Chang-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612045/
https://www.ncbi.nlm.nih.gov/pubmed/37896883
http://dx.doi.org/10.3390/v15102107