Cargando…

Diversity and Complexity of Internally Deleted Viral Genomes in Influenza A Virus Subpopulations with Enhanced Interferon-Inducing Phenotypes

Influenza A virus (IAV) populations harbor large subpopulations of defective-interfering particles characterized by internally deleted viral genomes. These internally deleted genomes have demonstrated the ability to suppress infectivity and boost innate immunity, rendering them promising for therape...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghorbani, Amir, Ngunjiri, John M., Rendon, Gloria, Brooke, Christopher B., Kenney, Scott P., Lee, Chang-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612045/ https://www.ncbi.nlm.nih.gov/pubmed/37896883 http://dx.doi.org/10.3390/v15102107

Ejemplares similares

Association between Interferon Response and Protective Efficacy of NS1-Truncated Mutants as Influenza Vaccine Candidates in Chickens
por: Jang, Hyesun, et al.
Publicado: (2016)

Efficacy and synergy of live-attenuated and inactivated influenza vaccines in young chickens
por: Jang, Hyesun, et al.
Publicado: (2018)

Influenza A virus infection in turkeys induces respiratory and enteric bacterial dysbiosis correlating with cytokine gene expression
por: Ngunjiri, John M., et al.
Publicado: (2021)

The presence of viral subpopulations in an infectious bronchitis virus vaccine with differing pathogenicity – A preliminary study
por: Hewson, Kylie A., et al.
Publicado: (2012)

Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis
por: Shim, Jung Min, et al.
Publicado: (2017)

Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Identification of the anti-viral activity as interferon and characterization of the human effector lymphocyte subpopulation
Publicado: (1978)

Chronic obstructive pulmonary disease subpopulations and phenotyping
por: Segal, Leopoldo N., et al.
Publicado: (2018)

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions
por: Liedmann, Swantje, et al.
Publicado: (2014)

Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses
por: Li, Ke, et al.
Publicado: (2023)

Interferons and viral infections
por: Higgins, P. G.
Publicado: (1984)

Biochemical Phenotypes to Discriminate Microbial Subpopulations and Improve Outbreak Detection
por: Galar, Alicia, et al.
Publicado: (2013)

In Vivo Assessment of NS1-Truncated Influenza Virus with a Novel SLSYSINWRH Motif as a Self-Adjuvanting Live Attenuated Vaccine
por: Ngunjiri, John M., et al.
Publicado: (2015)

Exclusion of latecomers yields a patchwork of viral subpopulations within hosts
por: Lowen, Anice C., et al.
Publicado: (2023)

Astrocytes produce interferon that enhances the expression of H-2 antigens on a subpopulation of brain cells
Publicado: (1986)

An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype
por: Bajad, Prajakta, et al.
Publicado: (2020)

Avian Toll-like receptor 3 isoforms and evaluation of Toll-like receptor 3–mediated immune responses using knockout quail fibroblast cells
por: KC, Mahesh, et al.
Publicado: (2020)

Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis
por: Rincón-Arévalo, Héctor, et al.
Publicado: (2016)

Interferon and Ocular Viral Disease
por: Galin, Miles A., et al.
Publicado: (1970)

Interferon, Mx, and viral countermeasures
por: Haller, Otto, et al.
Publicado: (2007)

Viral suppression of the interferon system
por: Weber, Friedemann, et al.
Publicado: (2007)

Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity
por: Sang, Yongming, et al.
Publicado: (2016)

Generation of Replication-Proficient Influenza Virus NS1 Point Mutants with Interferon-Hyperinducer Phenotype
por: Pérez-Cidoncha, Maite, et al.
Publicado: (2014)

Whence Interferon? Variety in the Production of Interferon in Response to Viral Infection
por: Levy, David E.
Publicado: (2002)

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export
por: Killip, Marian J., et al.
Publicado: (2014)

The Interferon-Induced Protein with Tetratricopeptide Repeats Repress Influenza Virus Infection by Inhibiting Viral RNA Synthesis
por: Zhu, Zhengyu, et al.
Publicado: (2023)

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
por: Specht, Christian G, et al.
Publicado: (2001)

Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity
por: Sun, Jiayi, et al.
Publicado: (2018)

Diverse drug-resistant subpopulations of Mycobacterium tuberculosis are sustained in continuous culture
por: Ayabina, Diepreye, et al.
Publicado: (2016)

Genetic diversity and relationship among indigenous Turkish Karayaka sheep subpopulations
por: Kirikci, Koray, et al.
Publicado: (2020)

Cancer-Associated Fibroblast Subpopulations With Diverse and Dynamic Roles in the Tumor Microenvironment
por: Simon, Thomas, et al.
Publicado: (2022)

Upregulated influenza A viral entry factors and enhanced interferon-alpha response in the nasal epithelium of pregnant rats
por: Giri, Tusar, et al.
Publicado: (2022)

Interferons: Signaling, antiviral and viral evasion
por: Bonjardim, Cláudio A., et al.
Publicado: (2009)

Interferons and Their Use in Persistent Viral Infections
por: Chevaliez, Stéphane, et al.
Publicado: (2009)

Viral Infections and Interferons in the Development of Obesity
por: Tian, Yun, et al.
Publicado: (2019)

Viral recognition and the antiviral interferon response
por: Dalskov, Louise, et al.
Publicado: (2023)

Influenza virus activation of the interferon system
por: Killip, Marian J., et al.
Publicado: (2015)

Phenotypic diversity in an international Cure VCP Disease registry
por: Ikenaga, Chiseko, et al.
Publicado: (2020)

Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO(2)-exposed rats
por: Garn, Holger, et al.
Publicado: (2006)

Unique sperm haplotypes are associated with phenotypically different sperm subpopulations in Astyanax fish
por: Borowsky, Richard, et al.
Publicado: (2018)

Phenotypically defined subpopulations of circulating follicular helper T cells in common variable immunodeficiency
por: Yesillik, Sait, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t770u31kijrr2jssbolkvpmm03