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The ‘speck’-tacular oversight of the NLRP3-pyroptosis pathway on gastrointestinal inflammatory diseases and tumorigenesis

The NLRP3 inflammasome is an intracellular sensor and an essential component of the innate immune system involved in danger recognition. An important hallmark of inflammasome activation is the formation of a single supramolecular punctum, known as a speck, per cell, which is the site where the pro-i...

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Detalles Bibliográficos
Autores principales: Arrè, Valentina, Scialpi, Rosanna, Centonze, Matteo, Giannelli, Gianluigi, Scavo, Maria Principia, Negro, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612184/
https://www.ncbi.nlm.nih.gov/pubmed/37891577
http://dx.doi.org/10.1186/s12929-023-00983-7