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Vitexin attenuates chronic kidney disease by inhibiting renal tubular epithelial cell ferroptosis via NRF2 activation

BACKGROUND: Chronic kidney disease (CKD) involves a variety of pathological processes, and ferroptosis plays a vital role in CKD progression. Targeting ferroptosis is a promising strategy for the treatment of CKD. However, inhibitors of ferroptosis have not been used in the clinical treatment of CKD...

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Detalles Bibliográficos
Autores principales: Song, Jiayu, Wang, Hongri, Sheng, Jingyi, Zhang, Wen, Lei, Juan, Gan, Weihua, Cai, Fangfang, Yang, Yunwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612207/
https://www.ncbi.nlm.nih.gov/pubmed/37891461
http://dx.doi.org/10.1186/s10020-023-00735-1