Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau

Distinctive post-translational modifications (PTM) characterize tau inclusions found in tauopathy patients. Using detergent-insoluble tau isolated from Alzheimer’s disease (AD-tau) or Progressive Supranuclear Palsy (PSP-tau) patients, we provide insights into whether phosphorylation of critical resi...

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Detalles Bibliográficos
Autores principales: Smith, Ethan D., Vo, Quan, Giasson, Benoit I., Borchelt, David R., Prokop, Stefan, Chakrabarty, Paramita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612232/
https://www.ncbi.nlm.nih.gov/pubmed/37891635
http://dx.doi.org/10.1186/s40478-023-01664-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612232/
https://www.ncbi.nlm.nih.gov/pubmed/37891635
http://dx.doi.org/10.1186/s40478-023-01664-0

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