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Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau

Distinctive post-translational modifications (PTM) characterize tau inclusions found in tauopathy patients. Using detergent-insoluble tau isolated from Alzheimer’s disease (AD-tau) or Progressive Supranuclear Palsy (PSP-tau) patients, we provide insights into whether phosphorylation of critical resi...

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Detalles Bibliográficos
Autores principales:	Smith, Ethan D., Vo, Quan, Giasson, Benoit I., Borchelt, David R., Prokop, Stefan, Chakrabarty, Paramita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612232/ https://www.ncbi.nlm.nih.gov/pubmed/37891635 http://dx.doi.org/10.1186/s40478-023-01664-0

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