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N6-methyladenosine-modified oncofetal lncRNA MIR4435-2HG contributed to stemness features of hepatocellular carcinoma cells by regulating rRNA 2′-O methylation

BACKGROUND: The unique expression pattern endows oncofetal genes with great value in cancer diagnosis and treatment. However, only a few oncofetal genes are available for clinical use and the underlying mechanisms that drives the fetal-like reprogramming of cancer cells remain largely unknown. METHO...

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Detalles Bibliográficos
Autores principales: Zhu, Yiqing, Xiao, Bang, Liu, Meng, Chen, Meiting, Xia, Ningqi, Guo, Haiyan, Huang, Jinfeng, Liu, Zhiyong, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612268/
https://www.ncbi.nlm.nih.gov/pubmed/37891494
http://dx.doi.org/10.1186/s11658-023-00493-2