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Limited effects of azithromycin on the oropharyngeal microbiome in children with CF and early pseudomonas infection

BACKGROUND: Tobramycin inhalation solution (TIS) and chronic azithromycin (AZ) have known clinical benefits for children with CF, likely due to antimicrobial and anti-inflammatory activity. The effects of chronic AZ in combination with TIS on the airway microbiome have not been extensively investiga...

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Detalles Bibliográficos
Autores principales: Wagner, Brandie D., Zemanick, Edith T., Sagel, Scott D., Robertson, Charles E., Stevens, Mark J., Mayer-Hamblett, Nicole, Retsch-Bogart, George, Ramsey, Bonnie W., Harris, J. Kirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612347/
https://www.ncbi.nlm.nih.gov/pubmed/37891457
http://dx.doi.org/10.1186/s12866-023-03073-8